A Natural Language Processing System for Automated Quality Assessment of Psychiatric Interviews in Clinical Research: A Case Study Based on BIPOVITE Clinical Trial

Scientific Context

Mental health research relies on standardized diagnostic interviews (MINI, SCID) conducted by multiple interviewers, introducing significant quality biases. The lack of automated quality control tools represents a major methodological bottleneck undermining clinical research data reliability.

Main Objective

To develop an innovative natural language processing (NLP) tool enabling standardized and automated qualitative auditing of clinical interviews in mental health.

Methodological Approach

Our interdisciplinary approach combines psychiatric expertise, computational linguistics, and machine learning through expert knowledge acquisition, algorithm development for expert behavior emulation, corpus annotation, model training and validation, and replication across multiple questionnaires (MINI, C-SSRS, MADRS).

Clinical Foundation

The project is anchored in the BIPOVITE study, a multicenter prospective observational study validating a composite medical device for bipolar disorder diagnosis. The study involves 623 adults and employs recorded questionnaires for quality assessment.

Innovation and Impact

The solution aims to reduce diagnostic biases and increase the early detection of protocol deviations. The approach transforms quality control from retrospective auditing to proactive assurance, enabling 24-hour assessment. Open-source development addresses the current lack of certified tools for automated quality assessment in psychiatric clinical trials.

See the demo
Work in progress - This project is currently seeking funding through the ANR AAPG 2026 call. The demo uses synthetic data for illustration purposes. Real-world data collection and model training will begin once the project is funded.